Cerebrovascular Flow Dynamics Research Laboratory

Cerebrovascular Flow Dynamics Research Laboratory, NICN

The Cerebrovascular Flow Dynamics Research Laboratory is operated by the collaboration of the Department of Neurointerventions of NICN and the Department of Hydrodynamic Systems at the Budapest University of Technology and Economics (BUTE). The primary aim of the Laboratory is the study the pathogenesis, natural history as well treatment of cerebrovascular pathology in lieu of the local hemodynamics, applying Computational Fluid Dynamics (CFD). Our research is based on 3D angiograms of real human vascular anatomy that is converted to finite volume model using proprietary software and used for CFD simulations. Physical features of endovascular tools used for interventional treatment are measured in experimental setup and their effect on flow is simulated on CFD models. Flow conditions of vascular pathologies are studied in relation to their morphology using image fusion of high resolution MR imaging and 3D angiography.

Our researchers:
Berentei Zs M.D., Marosfői M M.D., Gubucz M.D., (NICN), Paál Gy PhD, Ugron Á PhD, Závodczky G PhD, (BUTE), Szikora I PhD, Head of Laboratory

References:
Paal, G. Ugron A, Szikora I, Bojtar I: Flow in simplified and real models of intracranial aneurysms, Int. J. Heat Fluid Flow (2007), 28: 653-664

Istvan Szikora*, Gyorgy Paal**, Adam Ugron**, Ferenc Nasztanovics**, Miklos Marosfoi*, Zsolt Berentei*, Zsolt Kulcsar*, Wickly Lee*, Imre Bojtar**, Istvan Nyary*
Impact of aneurysmal geometry on intra-aneurysmal flow: a computerized flow simulation study. Neuroradiology, 2008, 50:411-421
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18180916

Szikora, P.K. Nelson, Z. Berentei, Z. Kulcsar. M. Marosfoi, A. Berez: The Potential of Flow Modification in the Treatment of Intracranial Aneurysms. Interventional Neuroradiology 14: 77-80, 2008
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20557779
 
Kulcsár Z, Ugron A, Marosfo I M, Berentei Z, Paál G, Szikora I.: Hemodynamics of Cerebral Aneurysm Initiation: The Role of Wall Shear Stress and Spatial Wall Shear Stress Gradient. AJNR Am J Neuroradiol. Mar 2011; 32: 587 – 594.
2011 Feb 10. [Epub ahead of print] DOI: ajnr.A2339 [pii]10.3174/ajnr.A2339.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21310860

Ugron, Á, Szikora, I, Paál, Gy: Hemodynamic changes induced by intrasaccular packing on intracranial aneurysms: a computational fluid dynamic study. Journal of Interventional Medicine and Applied Sciences, 4: 78-84, 2012

Actual

All those using our outpatient specialised care must first sign in at the desk located on the ground floor of the clinic. Here we record all your details into our computer system. For this we ask you to prepare your identity card, residence card, referral and your social security card. more...

science

Due to our visiting policies the relatives of our patients are able to visit daily. However, visiting hours are closed during patient care, treatments and examinations. In the interest of quick recovery, we ask that you not visit your relatives during quiet hours, and that when possible only two people visit at a time. more...

Education

According to the principles and the regulations of sequencing due waiting list, the basis is that you can be informed about expected date of intervention by using the identification number/code.
Waiting list were compiled related to the Health Ministry regulations and government regulation. more...